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SUMMARY:Powering the Future of Lentiviral Manufacturing: Continuous Perfusion for in vivo Cell and Gene Therapies
DESCRIPTION:Rachel Legmann Senior Director of Technology and Gene Therapy Repligen\nThe rapid expansion of in vivo gene and cell therapies is redefining lentiviral vector (LV) manufacturing requirements. Systemic delivery demands significantly higher vector quantities\, consistent quality\, and cost-effective scalability\, which traditional batch-based HEK293 transient transfection platforms were not designed to deliver. This presentation highlights how continuous\, scalable perfusion enables a transformative shift in LV manufacturing tailored for in vivo applications. We demonstrate a robust\, scalable platform capable of supporting large-scale (up to 2\,000 L) commercial manufacturing for in-vivo gene and cell therapies. \nhttps://go.ncsu.edu/btec_seminar
URL:https://btec.ncsu.edu/event/seminar-041026/
LOCATION:BTEC\, 850 Oval Drive\, Raleigh\, NC\, 27606\, United States
CATEGORIES:BTEC Seminar Series
ORGANIZER;CN="Danny Monroe%2C Ph.D.":MAILTO:dsmonroe@ncsu.edu
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