Content

Chromatography Column Packing: Foundations and Applications

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Delivery methods

Course content

downstream course

Downstream

This course can count toward your Professional Certificate in Biomanufacturing Science.

Why should you attend?

A well-packed chromatography column is critical to chromatographic separations. Low quality chromatography column packing leads to uneven mobile phase distribution and poor resin contacting ultimately leading to lower yields, less separation and reduced product quality. This course is designed to explain and demonstrate the factors that influence column packing from both a theoretical and hands-on perspective.

Attend and you will learn

  • Fluid mechanics of flow in packed beds
  • Theoretical basis of mass transfer in packed beds
  • The effects of incompressible versus compressible chromatography resin
  • Different packing techniques
  • Analytical methods for determining column packing quality
  • Packing parameter selection to ensure a robust, reproducible packing procedure

Who should attend

  • Production personnel responsible for column packing, writing packing procedures, and addressing column performance issues
  • Manufacturing science/technical services personnel responsible for writing packing procedures and addressing column performance issues
  • Process development scientists and engineers responsible for developing chromatography packing procedures or working with chromatographic columns at bench- and pilot-scale
  • Systems engineers interested in the design and handling aspects of columns based on production operations

Attend and you will receive

  • 18.5 hours of instruction
  • Notebook containing all course lecture and lab materials
  • Morning coffee and tea
  • Lunch
  • Afternoon beverage break
  • Certificate of completion

Instructors

John van Zanten, Ph.D.

Fee

$3,250

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