Downstream Biopharmaceutical Processes: Fundamentals and Design
Gain a deeper understanding of the fundamentals of recovery and purification operations for biopharmaceutical production and how these operations are designed for use at production scale. This course provides both theoretical and practical insight through lectures and laboratory activities.
| Dates | Course | Cost | Registration |
|---|---|---|---|
| May 12-13, 2026 | Artificial Intelligence in FDA-Regulated Manufacturing: From Foundations to Implementation | $1,500 | Register |
| May 20–21, 2026 | Hands-On Essentials of Automation for Biomanufacturing | $2,050 | Register |
| May 27–29, 2026 | Preparative Chromatography Column Packing: Lab to Process Scale | $2,500 | Register |
| June 3–4, 2026 | Applied Cleaning Validation Practices: A STERIS Master Class | $2,000 | Register |
| June 9–10, 2026 | Introduction to Biopharmaceutical Lyophilization | $1,975 | Register |
| June 11, 2026 | Essentials of Spray Drying and Powder Analysis | $995 | Register |
| June 16–18, 2026 | Fundamentals of Mammalian Cell Line Development | $3,100 | Register |
| June 23–25, 2026 | Biopharmaceutical Assay Essentials | $3,100 | Register |
| June 23–25, 2026 | Fermentation Engineering | $3,100 | Register |
| June 30–July 2, 2026 | Hands-On Principles of mRNA Technology | $2,500 | Register |
| July 8–10, 2026 | Downstream Biopharmaceutical Processes: Fundamentals and Design | $3,100 | Register |
| July 14–16, 2026 | AAV Quality Attributes: Theory and Practice | $2,975 | Register |
| July 14–17, 2026 | Hands-On cGMP Biomanufacturing Operations | $4,200 | Register |
| July 28–31, 2026 | Hands-On Biomanufacturing of Vectors for Gene Therapy | $4,500 | Register |
| Aug 6, 2026 | Design of Experiments for Biomanufacturing | $500* | Register |
| Sept 29–Oct 1, 2026 | Cell Culture Engineering | $4,200 | Register |
| Oct 13–16, 2026 | Applied Principles and Techniques of Depth Flow Filtration (DFF) and Tangential Flow Filtration (TFF) for BioPharm Purification | $3,995 | Register |
| Nov 10–12, 2026 | PAT for Real-time Culture Monitoring and Closed-Loop Process Control | $2,975 | Register |
| November 12-19 | Microbial Contamination Control in Bioprocessing Operations | $2,975 |
Attend and you will learn
- Theoretical and operational principles that underlie homogenization (and other cell lysis methods), centrifugation, chromatography, and tangential flow filtration—i.e., the downstream unit operations
- Regulatory expectations for design of downstream processing steps
- Experimental methods for determining process parameter ranges and material attributes (if applicable) for each unit operation
- Basic scale-up calculations and considerations for each operation
- How these unit operations come together to form an integrated process train for a variety of production scenarios, including intracellular products from E. coli, extracellular products from CHO, and inclusion body production
Delivery methods
40% Lecture
10% Discussion/group activity
50% Hands-on lab experience
Course content
50% Fundamentals and concepts
30% Industry applications
20% Emerging technologies
22.25 hours of instruction
Who should attend
The course covers material that is especially relevant to scientists and engineers (BS, MS, PhD, or equivalent experience) working in downstream biopharmaceutical process development, particularly those new to the field. But the course’s overview of fundamental principles and design considerations for all of the operations associated with downstream processing make it worthwhile for others to consider, including the following:
- Manufacturing managers interested in knowing more about how the processes in their suites are designed
- Process Validation staff involved in defining operating ranges and attribute specifications
- Quality assurance professionals that support downstream processes
- Vendors who supply the biomanufacturing industry with downstream equipment and components