Preparative Chromatography Column Packing: Lab to Process Scale
A well-packed chromatography column is critical to chromatographic separations at benchtop- and industrial-scales alike. Low-quality chromatography column packing can cause uneven mobile phase distribution and poor stationary phase contacting, ultimately leading to lower yields, less separation, and reduced product quality.
Designed for biotechnology, pharmaceutical, and biopharma downstream processing professionals, from those building core competencies to experienced individuals, this course is designed to explain and demonstrate the factors that influence column packing from both a theoretical and hands-on perspective.
This course is offered in collaboration with Bio-Rad Laboratories, Inc.
| Dates | Course | Cost | Registration |
|---|---|---|---|
| May 12-13, 2026 | Artificial Intelligence in FDA-Regulated Manufacturing: From Foundations to Implementation | $1,500 | Register |
| May 20–21, 2026 | Hands-On Essentials of Automation for Biomanufacturing | $2,050 | Register |
| May 27–29, 2026 | Preparative Chromatography Column Packing: Lab to Process Scale | $2,500 | Register |
| June 3–4, 2026 | Applied Cleaning Validation Practices: A STERIS Master Class | $2,000 | Register |
| June 9–10, 2026 | Introduction to Biopharmaceutical Lyophilization | $1,975 | Register |
| June 11, 2026 | Essentials of Spray Drying and Powder Analysis | $995 | Register |
| June 16–18, 2026 | Fundamentals of Mammalian Cell Line Development | $3,100 | Register |
| June 23–25, 2026 | Biopharmaceutical Assay Essentials | $3,100 | Register |
| June 23–25, 2026 | Fermentation Engineering | $3,100 | Register |
| June 30–July 2, 2026 | Hands-On Principles of mRNA Technology | $2,500 | Register |
| July 8–10, 2026 | Downstream Biopharmaceutical Processes: Fundamentals and Design | $3,100 | Register |
| July 14–16, 2026 | AAV Quality Attributes: Theory and Practice | $2,975 | Register |
| July 14–17, 2026 | Hands-On cGMP Biomanufacturing Operations | $4,200 | Register |
| July 28–31, 2026 | Hands-On Biomanufacturing of Vectors for Gene Therapy | $4,500 | Register |
| Aug 6, 2026 | Design of Experiments for Biomanufacturing | $500* | Register |
| Sept 29–Oct 1, 2026 | Cell Culture Engineering | $4,200 | Register |
| Oct 13–16, 2026 | Applied Principles and Techniques of Depth Flow Filtration (DFF) and Tangential Flow Filtration (TFF) for BioPharm Purification | $3,995 | Register |
| Nov 10–12, 2026 | PAT for Real-time Culture Monitoring and Closed-Loop Process Control | $2,975 | Register |
| TBD | Microbial Contamination Control in Bioprocessing Operations | $2,975 |
Register by May 12
Attend and you will learn
- Fluid mechanics of flow in packed beds
- Theoretical basis of mass transfer in packed beds
- Overview of downstream process development for biomanufacturing
- How to pack incompressible and compressible chromatography media
- Analytical methods for determining column packing quality
- Packing parameter selection to ensure a robust, reproducible packing procedure
Who should attend
- Production personnel responsible for column packing, writing packing procedures, and addressing column performance issues
- Manufacturing science/technical services personnel responsible for writing packing procedures and addressing column performance issues
- Process development scientists and engineers responsible for developing chromatography packing procedures or working with chromatographic columns at bench, pilot, and process/manufacturing scales
- Systems engineers interested in the design and handling aspects of columns based on production operations
Instructors
- John van Zanten, Ph.D.
- Young Li, Ph.D.
Field Application Scientist, Process Chromatography, Bio-Rad Laboratories, Inc.
Young Li received his Ph.D. degree in biochemistry from Kyoto University and conducted postdoctoral trainings at the NIH in biochemistry and x-ray crystallography. He is specialized in protein engineering, molecular biology, and downstream purification process development with more than 25 years of industrial experiences in biotech and pharmaceutical companies including ChemGen, IAVI, Elanco, Eli Lilly, and Uvax Bio where he led protein purification, PD, and R&D groups for drug development. - Erik Verona, Ph.D.
Field Application Scientist, Process Chromatography, Bio-Rad Laboratories, Inc.
Erik Verona received his Ph.D. degree in biomedical sciences from the University of Texas Health Science Center at San Antonio where he continued with his postdoctoral work on a recombinant chimeric receptor protein that blocks signaling of all three isoforms of transforming growth factor beta. Erik has over 25 years of R&D experience including cell and tissue culture, cancer biology, bacteriology, blood fractionation, and all aspects of recombinant protein production and purification. His industry experience includes roles at Chiron, Genentech, INCELL, Cone Bioproducts, and Terapio where he led the upstream, downstream and formulation process development for a recombinant protein radiation countermeasure.