Hands-On Principles of mRNA Technology
mRNA technology is transforming the landscape of modern medicine, driving innovations in vaccines and various therapies. The demand for skilled professionals who understand mRNA design, synthesis, and manufacturing has grown rapidly. This course provides a practical foundation in the science and production of mRNA therapeutics, preparing participants to contribute to this fast-evolving and impactful field.
| Dates | Course | Cost | Registration |
|---|---|---|---|
| May 12-13, 2026 | Artificial Intelligence in FDA-Regulated Manufacturing: From Foundations to Implementation | $1,500 | Register |
| May 20–21, 2026 | Hands-On Essentials of Automation for Biomanufacturing | $2,050 | Register |
| May 27–29, 2026 | Preparative Chromatography Column Packing: Lab to Process Scale | $2,500 | Register |
| June 3–4, 2026 | Applied Cleaning Validation Practices: A STERIS Master Class | $2,000 | Register |
| June 9–10, 2026 | Introduction to Biopharmaceutical Lyophilization | $1,975 | Register |
| June 11, 2026 | Essentials of Spray Drying and Powder Analysis | $995 | Register |
| June 16–18, 2026 | Fundamentals of Mammalian Cell Line Development | $3,100 | Register |
| June 23–25, 2026 | Biopharmaceutical Assay Essentials | $3,100 | Register |
| June 23–25, 2026 | Fermentation Engineering | $3,100 | Register |
| June 30–July 2, 2026 | Hands-On Principles of mRNA Technology | $2,500 | Register |
| July 8–10, 2026 | Downstream Biopharmaceutical Processes: Fundamentals and Design | $3,100 | Register |
| July 14–16, 2026 | AAV Quality Attributes: Theory and Practice | $2,975 | Register |
| July 14–17, 2026 | Hands-On cGMP Biomanufacturing Operations | $4,200 | Register |
| July 28–31, 2026 | Hands-On Biomanufacturing of Vectors for Gene Therapy | $4,500 | Register |
| Aug 6, 2026 | Design of Experiments for Biomanufacturing | $500* | Register |
| Sept 29–Oct 1, 2026 | Cell Culture Engineering | $4,200 | Register |
| Oct 13–16, 2026 | Applied Principles and Techniques of Depth Flow Filtration (DFF) and Tangential Flow Filtration (TFF) for BioPharm Purification | $3,995 | Register |
| Nov 10–12, 2026 | PAT for Real-time Culture Monitoring and Closed-Loop Process Control | $2,975 | Register |
| TBD | Microbial Contamination Control in Bioprocessing Operations | $2,975 |
Register by June 15
Course Learning Objectives
At the end of this course, participants should be able to:
- Explain the principles of mRNA biology and its role in vaccines and therapeutic applications.
- Design mRNA constructs by understanding key structural elements and codon optimization strategies.
- Describe and execute the main steps in mRNA manufacturing, including plasmid preparation and linearization, mRNA in vitro transcription, mRNA capping, purification and formulation with lipidic nanoparticles (LNP).
- Demonstrate the ability to generate a plasmid DNA template and perform its purification using manual small-column techniques and automated chromatography on an ÄKTA system.
- Apply analytical and chromatographic methods (HPLC, ddPCR, electrophoresis) to assess product quality and purity.
- Evaluate mRNA functionality through cell transfection and protein expression analysis.
- Understand how the BioSMB system performs continuous purification of plasmid DNA and appreciate its advantages for scalability and process intensification in modern mRNA biomanufacturing.
- Discuss key quality control parameters ensuring mRNA safety, integrity, and regulatory compliance.
Who Should Attend
- Process development and manufacturing engineers in mRNA upstream or downstream operations
- Quality control and analytical scientists
- Academic researchers and students in biotechnology or molecular biology
- Technical sales and business professionals seeking a solid introduction to mRNA technology and its manufacturing workflow
- Regulatory agents involved in biologics or vaccine oversight
Instructors
- Driss Elhanafi, Ph.D.
- Danny Schmitt
- Arjun Shastry, Scientist II, Bioprocess Services
- Mark Stoops, Scientist I, Analytical Development