Gain a deeper understanding of the fundamentals of recovery and purification operations for biopharmaceutical production and how these operations are designed for use at production scale. This course provides both theoretical and practical insight through lectures and laboratory activities.
Take this course to experience a 3-day, hands-on, overview of AAV Quality Attributes. Step through each CQA category, Identity, Quantity, Potency, Purity and Safety through interactive lectures, group workshops, and hands-on labs in BTEC’s state of the art facility. All course content is directly related to current applications in industry while providing basic theory to…
Obtain a basic knowledge of biomanufacturing operations and how CGMP requirements are implemented at commercial scale. Engage in pilot-scale laboratory experiences that examine process utilities, media and solution preparation, bioreactor operation, centrifugation, chromatography, and tangential flow filtration in a simulated commercial CGMP (current Good Manufacturing Practice) facility.
Obtain hands-on training in the production of vectors for gene therapy products using an AAV2-GFP model system in both HEK293 cells and Sf9/Baculovirus systems. Engage in pilot/manufacturing-scale upstream operations (adherent and suspension cell culture, vector production scale-up in cell stacks and single-use bioreactors); downstream operations (cell lysis, product recovery via depth filtration, purification using chromatography,…
This workshop aims to introduce participants to the principles and applications of Design of Experiments (DoE) in the analysis of bioprocesses. Through a combination of lectures, hands-on use of JMP statistical software (SAS Institute), and real bioprocess case studies, attendees will learn how to apply DoE techniques in practice. The case studies, centered on microbial…
Learn key concepts and practical skills in bioprocess development and cell culture engineering in biomanufacturing. Lectures focus on cell culture media and feeding strategies, operational modes (batch, fed-batch, perfusion), bioreactor design (single-use and stainless steel), high-density cell banking, critical process controls, harvest operations, design of experiments (DOE) in process development, glycan analysis by mass spectrometry,…
By participating in this comprehensive four-day filtration course, you will gain a solid understanding of the core principles and best practices for both depth filtration (DFF) and tangential flow filtration (TFF) as applied in modern biopharmaceutical upstream and downstream purification processes. This program is designed to equip you with practical skills and insights that can…
In this three-day, hands-on course, you will gain familiarity with and applied insight into the functionality of control equipment and instrumentation, and how to integrate Process Analytical Technology (PAT) into a model yeast fermentation for more advanced in-line monitoring and process control. Participants will work with traditional sensors, a PAT spectral sensor, and multivariate data…